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4'-Hydroxyvalerophenone

4'-Hydroxyvalerophenone (Compound 4) is an inhibitor of 17β-hydroxysteroid dehydrogenase (17β-HSD) with an IC50 of 60.52 μM[1].

Product Specifications

CAS Number

[2589-71-1]

Product Name Alternative

4-Pentanoylphenol; 4-Valerylphenol

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

17β-HSD

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/4-hydroxyvalerophenone.html

Purity

99.96

Solubility

10 mM in DMSO

Smiles

CCCCC(C1=CC=C(O)C=C1)=O

Molecular Formula

C11H14O2

Molecular Weight

178.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Lota RK, et al. Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-hydroxyphenyl ketones as potential inhibitors of 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3) . Bioorg Med Chem Lett. 2006 Sep 1;16 (17) :4519-22.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W016604/4-Hydroxyvalerophenone-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W016604/4-Hydroxyvalerophenone-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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