Lucidadiol

Lucidadiol is a natural compound isolated from Ganoderma lucidum. Lucidadiol exhibits acetylcholinesterase-inhibitory activity, with IC50 values of 31 μM. Lucidadiol shows antiviral activity against influenza virus type A and HSV type 1[1][2].

Product Specifications

CAS Number

[252351-95-4]

UNSPSC

12352211

Target

Cholinesterase (ChE) ; HSV

Type

Natural Products

Related Pathways

Anti-infection; Neuronal Signaling

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/lucidadiol.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

CC(C)([C@](C1)2[H])[C@@H](O)CC[C@]2(C)C3=C([C@@]4(CC[C@@H]([C@]4(CC3)C)[C@H](C)CC/C=C(C)/CO)C)C1=O

Molecular Formula

C30H48O3

Molecular Weight

456.70

References & Citations

[1]Iksoo Lee, et al. Selective cholinesterase inhibition by lanostane triterpenes from fruiting bodies of Ganoderma lucidum. Bioorg Med Chem Lett. 2011 Nov 1;21 (21) :6603-7.|[2]Lee I, et al. Selective cholinesterase inhibition by lanostane triterpenes from fruiting bodies of Ganoderma lucidum [published correction appears in Bioorg Med Chem Lett. 2013 Nov 15;23 (22) :6199-200]. Bioorg Med Chem Lett. 2011;21 (21) :6603-6607.|[3]Mothana RA, et al. Antiviral lanostanoid triterpenes from the fungus Ganoderma pfeifferi. Fitoterapia. 2003;74 (1-2) :177-180.