Ganglioside GD2

Ganglioside GD2 (Disialoganglioside GD2), a member of the ganglioside family, is a tumor-associated antigen that is highly expressed in almost all neuroblastomas, as well as in most melanomas and retinoblastomas. Ganglioside GD2 contributes to tumor development by enhancing cell proliferation, motility, migration, adhesion, and invasion. Anti-Ganglioside GD2 strategies hold promise for research in the field of anti-tumor therapy[1].

Product Specifications

CAS Number

[65988-71-8]

Product Name Alternative

Disialoganglioside GD2

UNSPSC

12352211

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ganglioside-gd2.html

Purity

97.04

Smiles

O=C([C@]1(OC[C@@H](O)[C@H]([C@H]2O[C@](C(O)=O)(O[C@@H]3[C@@H](O)[C@H](O[C@@H]4[C@@H](CO)O[C@@H](OC[C@H](NC(CCCCCCCCCCCCCCCCC)=O)[C@H](O)/C=C/CCCCCCCCCCCCC)[C@H](O)[C@H]4O)O[C@H](CO)[C@@H]3O[C@@H]5O[C@H](CO)[C@H](O)[C@H](O)[C@H]5NC(C)=O)C[C@@H](O)[C@@H]2NC(C)=O)O)O[C@H]([C@H](O)[C@H](O)CO)[C@@H](NC(C)=O)[C@H](O)C1)O

Molecular Formula

C78H138N4O34

Molecular Weight

1675.94

References & Citations

[1]Nazha B, et al. Disialoganglioside GD2 Expression in Solid Tumors and Role as a Target for Cancer Therapy. Front Oncol. 2020 Jul 7;10:1000. doi: 10.3389/fonc.2020.01000.