HCV-IN-45
HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread[1].
Product Specifications
CAS Number
301211-35-8
UNSPSC
12352005
Target
HCV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hcv-in-45.html
Smiles
FC(F)(COC1=NC(NC2=CC=C(C=C2)[N+]([O-])=O)=NC(NCCCCC)=N1)F
Molecular Formula
C16H19F3N6O3
Molecular Weight
400.36
References & Citations
[1]Baldick CJ, et al., A novel small molecule inhibitor of hepatitis C virus entry. PLoS Pathog. 2010 Sep 2;6 (9) :e1001086.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
46472061 1.0 µg DNA
TECR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details K3469706 1.0 µg DNA
Psma4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details M2350-01D-PE 100 µL
MAP2a, b (Microtubule Associated Protein 2a, b) (PE) discontinued
Sign In for Pricing
View Details