HCV-IN-45
HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread[1].
Product Specifications
CAS Number
301211-35-8
UNSPSC
12352005
Target
HCV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hcv-in-45.html
Smiles
FC(F)(COC1=NC(NC2=CC=C(C=C2)[N+]([O-])=O)=NC(NCCCCC)=N1)F
Molecular Formula
C16H19F3N6O3
Molecular Weight
400.36
References & Citations
[1]Baldick CJ, et al., A novel small molecule inhibitor of hepatitis C virus entry. PLoS Pathog. 2010 Sep 2;6 (9) :e1001086.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
