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2,3-Dihydroisoginkgetin

2,3-Dihydroisoginkgetin, a biflavonoid, is a inhibitor of Tyrosinase, with 36.84% inhibition at 0.1 mM. 2,3-Dihydroisoginkgetin shows less toxicity in HEMn (human epidermal melanocytes) cells, with an IC50 of 86.16 μM[1].

Product Specifications

CAS Number

828923-27-9

UNSPSC

12352005

Target

Tyrosinase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-3-dihydroisoginkgetin.html

Solubility

10 mM in DMSO

Smiles

O=C1C[C@@H](C2=CC=C(OC)C(C3=C4C(C(C=C(C5=CC=C(OC)C=C5)O4)=O)=C(O)C=C3O)=C2)OC6=CC(O)=CC(O)=C16

Molecular Formula

C32H24O10

Molecular Weight

568.53

References & Citations

[1]Cheng KT, et al. New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes. Chem Pharm Bull (Tokyo) . 2007 May;55 (5) :757-61.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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