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NNC 11-1607

NNC 11-1607 is a selective M1/M4 muscarinic acetylcholine receptor (mAChR) agonist. NNC 11-1607 inhibits Forskolin -stimulated cAMP accumulation in Chinese hamster ovary cells expressing the human M2 or M4 mAChR. NNC 11-1607 is promising for research of central nervous system disorders, such as Alzheimer’s disease and schizophrenia[1].

Product Specifications

CAS Number

250649-13-9

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nnc-11-1607.html

Smiles

C1(C#CCOC2=NSN=C2[C@@H]3CN4CCC3CC4)=CC=CC(C#CCOC5=NSN=C5[C@@H]6CN7CCC6CC7)=C1

Molecular Formula

C30H32N6O2S2

Molecular Weight

572.74

References & Citations

[1]Christopoulos A, et al. Synthesis and pharmacological evaluation of dimeric muscarinic acetylcholine receptor agonists. J Pharmacol Exp Ther. 2001 Sep;298 (3) :1260-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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