Erdafitinib (Standard)
Erdafitinib (Standard) is the analytical standard of Erdafitinib. This product is intended for research and analytical applications. Erdafitinib (JNJ-42756493) is a potent and orally available FGFR family inhibitor; inhibits FGFR1/2/3/4 with IC50s of 1.2, 2.5, 3.0 and 5.7 nM, respectively.
Product Specifications
CAS Number
1346242-81-6
Product Name Alternative
JNJ-42756493 (Standard)
UNSPSC
12352005
Target
Apoptosis; FGFR; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erdafitinib-standard.html
Smiles
CN1N=CC(C2=NC3=CC(N(C4=CC(OC)=CC(OC)=C4)CCNC(C)C)=CC=C3N=C2)=C1
Molecular Formula
C25H30N6O2
Molecular Weight
446.54
References & Citations
[1]Perera TP, et al. Discovery and pharmacological characterization of JNJ-42756493 (erdafitinib), a functionally selective small molecule FGFR family inhibitor. Mol Cancer Ther. 2017 Mar 24. pii: molcanther.0589.2016.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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