Tanfanercept
Tanfanercept (HL036337) is an TNF-α receptor fusion protein that targets TNF-α. Tanfanercept is effective in ameliorating corneal erosions in a dry eye (DE) mouse model[1][2].
Product Specifications
CAS Number
2119738-70-2
Product Name Alternative
HL036337; HBM9036
UNSPSC
12352203
Target
TNF Receptor
Type
Inhibitory Antibodies
Related Pathways
Apoptosis
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tanfanercept.html
Solubility
10 mM in DMSO
Smiles
[Tanfanercept]
References & Citations
[1]Choi W, et al. The Effect of TNF-α Blocker HL036337 and Its Best Concentration to Inhibit Dry Eye Inflammation. Korean J Ophthalmol. 2016 Aug;30 (4) :302-8. |[2]Dong Y, et al. TNF-α inhibitor tanfanercept (HBM9036) improves signs and symptoms of dry eye in a phase 2 trial in the controlled adverse environment in China. Int Ophthalmol. 2022 Aug;42 (8) :2459-2472.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Frequently Asked Questions
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