Tanfanercept

Tanfanercept (HL036337) is an TNF-α receptor fusion protein that targets TNF-α. Tanfanercept is effective in ameliorating corneal erosions in a dry eye (DE) mouse model[1][2].

Product Specifications

CAS Number

[2119738-70-2]

Product Name Alternative

HL036337; HBM9036

UNSPSC

12352203

Target

TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Apoptosis

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tanfanercept.html

Solubility

10 mM in DMSO

Smiles

[Tanfanercept]

References & Citations

[1]Choi W, et al. The Effect of TNF-α Blocker HL036337 and Its Best Concentration to Inhibit Dry Eye Inflammation. Korean J Ophthalmol. 2016 Aug;30 (4) :302-8. |[2]Dong Y, et al. TNF-α inhibitor tanfanercept (HBM9036) improves signs and symptoms of dry eye in a phase 2 trial in the controlled adverse environment in China. Int Ophthalmol. 2022 Aug;42 (8) :2459-2472.