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(-) -Hydroxycitric acid lactone (Standard)

(-) -Hydroxycitric acid lactone (Standard) is the analytical standard of (-) -Hydroxycitric acid lactone. This product is intended for research and analytical applications. (-) -Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-) -Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-) -Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis[1][2].

Product Specifications

CAS Number

27750-13-6

Product Name Alternative

Garcinia lactone (Standard)

UNSPSC

12352005

Target

ATP Citrate Lyase; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/minus-hydroxycitric-acid-lactone-standard.html

Smiles

O[C@](CC(O1)=O)(C(O)=O)[C@H]1C(O)=O

Molecular Formula

C6H6O7

Molecular Weight

190.11

References & Citations

[1]Han J, et al. (-) -Hydroxycitric acid reduced fat deposition via regulating lipid metabolism-related geneexpression in broiler chickens. Lipids Health Dis. 2016 Feb 24;15:37.|[2]Jena BS, et al. Chemistry and biochemistry of (-) -hydroxycitric acid from Garcinia. J Agric Food Chem. 2002 Jan 2;50 (1) :10-22.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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