Human Heparin Cofactor II

<strong>Human Heparin Cofactor II</strong>_x000D_ <strong>Catalog number:</strong> B2016641_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 65600_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> Human Heparin Cofactor II_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong> _x000D_ 1: Tollefsen DM. Heparin cofactor II Adv Exp Med Biol. 1997;425:35-44. _x000D_ 2: Tollefsen DM. Heparin cofactor II deficiency Arch Pathol Lab Med. 2002 Nov;126(11):1394-400. _x000D_ 3: Shimabukuro M. MAFLD and ASCVD: Plasma Heparin Cofactor II Activity as an Anti-liver Fibrosis Biomarker J Atheroscler Thromb. 2023 Aug 1;30(8):853-854. _x000D_ 4: Saito A. Heparin cofactor II is degraded by heparan sulfate and dextran sulfate Biochem Biophys Res Commun. 2015 Feb 20;457(4):585-8. _x000D_ 5: Bano S, Fatima S, Ahamad S, Ansari S, Gupta D, Tabish M, Rehman SU, Jairajpuri MA. Identification and characterization of a novel isoform of heparin cofactor II in human liver IUBMB Life. 2020 Oct;72(10):2180-2193. _x000D_ 6: Bano S, Khan AB, Fatima S, Rashid Q, Prakash A, Gupta N, Ahmad I, Ansari S, Lynn AM, Abid M, Jairajpuri MA. Mannose 2, 3, 4, 5, 6-O-pentasulfate (MPS): a partial activator of human heparin_cofactor II with anticoagulation potential J Biomol Struct Dyn. 2023 Jun;41(9):3717-3727. _x000D_ 7: Rau JC, Mitchell JW, Fortenberry YM, Church FC. Heparin_cofactor II: discovery, properties, and role in controlling vascular homeostasis Semin Thromb Hemost. 2011 Jun;37(4):339-48. _x000D_ 8: Aihara K. Heparin cofactor II attenuates vascular remodeling in humans and mice Circ J. 2010 Aug;74(8):1518-23. _x000D_ 9: Tollefsen DM. Vascular dermatan sulfate and heparin cofactor II Prog Mol Biol Transl Sci. 2010;93:351-72. _x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/17194895">10: Tollefsen DM. Heparin cofactor II modulates the response to vascular injury Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):454-60. </a>_x000D_ <br><strong>Products Related to Human Heparin Cofactor II can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>