Cyclocommunol
Cyclocommunol is a prenylflavonoid with antityrosinase and antiplatelet activitie, can be solated from breadfruit. Cyclocommunol exerts anti-tumor activity and inhibits the growth of human hepatoma and gastric cancer cells with IC50 values between 16 and 80 µM. Cyclocommunol shows proapoptotic effect on oral squamous cell carcinoma (OSCC) [1].
Product Specifications
CAS Number
145643-96-5
UNSPSC
12352005
Target
Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyclocommunol.html
Solubility
10 mM in DMSO
Smiles
C/C(C)=C\C1C2=C(OC3=C(C(O)=CC(O)=C3)C2=O)C4=CC=C(O)C=C4O1
Molecular Formula
C20H16O6
Molecular Weight
352.34
References & Citations
[1]Weng JR, et al. Cyclocommunol induces apoptosis in human oral squamous cell carcinoma partially through a Mcl-1-dependent mechanism. Phytomedicine. 2018 Jan 15;39:25-32.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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