Anti-KLK3 Antibody

Rabbit Polyclonal Antibody specific to KLK3

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

PSA, EC 3.4.21.77, γ-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase

Gene Name

KLK3

NCBI Gene ID

UniProt

P07288

Cellular Locus

Secreted.

Host

Rabbit

Reactivity

Human

Immunogen

Peptide corresponding to aa 247-261 of human KLK3 protein.

Target Antigen

Prostate-specific antigen

Target

KLK3

Clonality

Polyclonal

Type

Antibody

Applications

Field of Research

Cancer research

Purification Method

Purified by immunoaffinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium which is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Additionnal Information

Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 30 kD is detected.

Storage Conditions

This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze-thaw cycles.

Specificity

This antibody recognizes human KLK3 (prostate specific antigen, PSA), one of the many kallikrein serine proteases associated with carcinogenesis. KLK3 is a specific marker for prostate carcinoma that has also been associated with breast cancer and possibly other cancers.