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Human MBL2 Recombinant Rabbit Monoclonal Antibody [PSH04-85] - BSA and Azide free (Capture)

Mannose-binding lectin (MBL), also called mannan-binding lectin or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity as an opsonin and via the lectin pathway. MBL belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL recognizes carbohydrate patterns found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. Binding of MBL to a micro-organism results in activation of the lectin pathway of the complement system. Another important function of MBL is that this molecule binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes.

Product Specifications

Product Name Alternative

COLEC 1 antibody COLEC1 antibody Collectin-1 antibody HSMBPC antibody Lectin, mannose-binding, soluble, 2 antibody Mannan binding lectin antibody Mannan binding protein antibody Mannan-binding protein antibody Mannose binding lectin (protein C) 2 soluble antibody Mannose binding lectin (protein C) 2, soluble (opsonic defect) antibody Mannose binding lectin (protein C) 2, soluble antibody Mannose binding lectin 2 soluble antibody Mannose binding lectin 2, soluble (opsonic defect) antibody Mannose binding lectin antibody Mannose binding lectin protein C2 soluble opsonic defect antibody Mannose binding protein antibody Mannose binding protein C antibody Mannose binding protein C precursor antibody Mannose binding protein, serum antibody Mannose-binding lectin antibody Mannose-binding protein C antibody MBL 2 antibody MBL antibody MBL2 antibody MBL2_HUMAN antibody MBL2D antibody MBP 1 antibody MBP antibody MBP C antibody MBP-C antibody MBP1 antibody MBPB antibody MBPC antibody MBPD antibody MGC116832 antibody MGC116833 antibody Opsonic defect antibody protein C antibody Soluble mannose binding lectin antibody

Abbreviation

Mannose-binding protein C MBP-C Collectin-1 MBP1 Mannan-binding protein Mannose-binding lectin MBL2 COLEC1 MBL

Swiss Prot

P11226 Human

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human MBL2 aa 108-248 (P11226).

Isotype

IgG

Clone

PSH04-85

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

ELISA (Cap)

Positive Control

Recombinant Human MBL2 protein (HA210628).

Concentration

1 mg/mL

Dilution

ELISA (Cap): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH04-86] to Human MBL2 (Detector) (HA722192) and recombinant standard Human MBL2 protein (HA210628). The reference range value is 99-8000 pg/ml.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4).

Molecular Weight

Predicted band size: 26 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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