Rostratin C

Rostratin C, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC50 value of 0.76μg /mL[1].

Product Specifications

CAS Number

[752236-18-3]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rostratin-c.html

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@]([C@H]([C@H]2OC)O)([H])[C@](C(C2)=O)([H])C3)[C@@]4(SS[C@]13C5=O)N5[C@]([C@H]([C@H]6OC)O)([H])[C@](C(C6)=O)([H])C4

Molecular Formula

C20H24N2O8S2

Molecular Weight

484.54

References & Citations

[1]Tan RX, et al. Isolation and structure assignments of rostratins A-D, cytotoxic disulfides produced by the marine-derived fungus Exserohilum rostratum. J Nat Prod. 2004;67 (8) :1374-1382.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Microbial Metabolite

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