(R) -Alyssin
(R) -Alyssin is a enantiomer of Alyssin (HY-116920) . Alyssin, found in Cruciferous Vegetables, exerts anticancer activity in HepG2 by increasing intracellular reactive oxygen species and tubulin depolymerization[1].
Product Specifications
CAS Number
[167963-06-6]
UNSPSC
12352211
Target
Microtubule/Tubulin; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-alyssin.html
Smiles
O=[S@@](CCCCCN=C=S)C
Molecular Formula
C7H13NOS2
Molecular Weight
191.31
References & Citations
[1]Misiewicz I, et al. Differential response of human healthy lymphoblastoid and CCRF-SB leukemia cells to sulforaphane and its two analogues: 2-oxohexyl isothiocyanate and alyssin. Pharmacol Rep. 2007 Jan-Feb;59 (1) :80-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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