(R) -Alyssin

(R) -Alyssin is a enantiomer of Alyssin (HY-116920) . Alyssin, found in Cruciferous Vegetables, exerts anticancer activity in HepG2 by increasing intracellular reactive oxygen species and tubulin depolymerization[1].

Product Specifications

CAS Number

[167963-06-6]

UNSPSC

12352211

Target

Microtubule/Tubulin; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/r-alyssin.html

Smiles

O=[S@@](CCCCCN=C=S)C

Molecular Formula

C7H13NOS2

Molecular Weight

191.31

References & Citations

[1]Misiewicz I, et al. Differential response of human healthy lymphoblastoid and CCRF-SB leukemia cells to sulforaphane and its two analogues: 2-oxohexyl isothiocyanate and alyssin. Pharmacol Rep. 2007 Jan-Feb;59 (1) :80-7.