LGnRH-III, lamprey
LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities[1][2].
Product Specifications
CAS Number
147859-97-0
UNSPSC
12352209
Hazard Statement
H302-H315-H319-H335
Target
GnRH Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lgnrh-iii-lamprey.html
Purity
99.80
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)C(NCC(N)=O)=O)[C@H](CCCCN)NC([C@@H](NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@@H](NC([C@@H]2CCC(N2)=O)=O)CC3=CN=CN3)=O)CC4=CNC5=CC=CC=C45)=O)=O)CC6=CN=CN6)=O)=O)CC7=CNC8=CC=CC=C78)=O
Molecular Formula
C59H74N18O14
Molecular Weight
1259.33
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Pappa EV, et al. Structure-activity studies of lGnRH-III through rational amino acid substitution and NMR conformational studies. Biopolymers. 2012;98 (6) :525-34.|[2]Manea M, et al. lGnRH-III -- a promising candidate for anticancer drug development. Protein Pept Lett. 2013 Apr;20 (4) :439-49.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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