LGnRH-III, lamprey

LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities[1][2].

Product Specifications

CAS Number

[147859-97-0]

UNSPSC

12352209

Hazard Statement

H302-H315-H319-H335

Target

GnRH Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lgnrh-iii-lamprey.html

Purity

99.80

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@@H](CCC1)C(NCC(N)=O)=O)[C@H](CCCCN)NC([C@@H](NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@@H](NC([C@@H]2CCC(N2)=O)=O)CC3=CN=CN3)=O)CC4=CNC5=CC=CC=C45)=O)=O)CC6=CN=CN6)=O)=O)CC7=CNC8=CC=CC=C78)=O

Molecular Formula

C59H74N18O14

Molecular Weight

1259.33

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Pappa EV, et al. Structure-activity studies of lGnRH-III through rational amino acid substitution and NMR conformational studies. Biopolymers. 2012;98 (6) :525-34.|[2]Manea M, et al. lGnRH-III -- a promising candidate for anticancer drug development. Protein Pept Lett. 2013 Apr;20 (4) :439-49.