Recombinant Human ULK1 Protein (GST Tag, Active)

<strong>Recombinant Human ULK1 Protein (GST Tag, Active)</strong>_x000D_ <strong>Catalog number:</strong> B2018978_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ~125 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −80°C_x000D_ <strong>Keywords:</strong> ATG1 Protein, Human; ATG1A Protein, Human; hATG1 Protein, Human; KIAA0722 Protein, Human; UNC51 Protein, Human; Unc51.1 Protein, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Zhao YG, Chen Y, Miao G, Zhao H, Qu W, Li D, Wang Z, Liu N, Li L, Chen S, Liu P, Feng D, Zhang H. The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation Mol Cell. 2017 Sep 21;67(6):974-989.e6._x000D_ 2: Zhang H, Cui Z, Cheng D, Du Y, Guo X, Gao R, Chen J, Sun W, He R, Ma X, Peng Q, Martin BN, Yan W, Rong Y, Wang C. RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis Autophagy. 2021 Oct;17(10):3030-3047._x000D_ 3: Karanasios E, Stapleton E, Manifava M, Ktistakis NT. Imaging autophagy Curr Protoc Cytom. 2014 Jul 1;69:12.34.1-12.34.16._x000D_ 4: Qi S, Kim DJ, Stjepanovic G, Hurley JH. Structure of the Human Atg13-Atg101 HORMA Heterodimer: an Interaction Hub within the ULK1 Complex Structure. 2015 Oct 6;23(10):1848-1857._x000D_ 5: Wu SY, Du YC, Yue CF. Sirt7 protects chondrocytes degeneration in osteoarthritis via autophagy activation Eur Rev Med Pharmacol Sci. 2020 Sep;24(18):9246-9255._x000D_ 6: Li W, Yang Y, Ba Z, Li S, Chen H, Hou X, Ma L, He P, Jiang L, Li L, He R, Zhang L, Feng D. MicroRNA-93 Regulates Hypoxia-Induced Autophagy by Targeting ULK1 Oxid Med Cell Longev. 2017;2017:2709053._x000D_ 7: Lu H, Xiao J, Ke C, Ni X, Xiu R, Tian Q, Pan H, Zou L, Wang F, Ma T, Ji X, Yuan P, Liu L, Zhang J, Jia W, Duan Q, Zhu F. TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ Cell Death Dis. 2019 Aug 5;10(8):583._x000D_ 8: Ber Y, Shiloh R, Gilad Y, Degani N, Bialik S, Kimchi A. DAPK2 is a novel regulator of mTORC1 activity and autophagy Cell Death Differ. 2015 Mar;22(3):465-75._x000D_ 9: Ahwazi D, Neopane K, Markby GR, Kopietz F, Ovens AJ, Dall M, Hassing AS, Gräsle P, Alshuweishi Y, Treebak JT, Salt IP, Göransson O, Zeqiraj E, Scott JW, Sakamoto K. Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965 Biochem J. 2021 Aug 13;478(15):2977-2997._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30459284">10: Saleiro D, Blyth GT, Kosciuczuk EM, Ozark PA, Majchrzak-Kita B, Arslan AD, Fischietti M, Reddy NK, Horvath CM, Davis RJ, Fish EN, Platanias LC. IFN-γ-inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5 Sci Signal. 2018 Nov 20;11(557):eaap9921. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human ULK1 Protein (GST Tag, Active) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>