What is the catalog number for PCC16 (chloride)?

The catalog number for PCC16 (chloride) is HY-169232.

What sizes are available for PCC16 (chloride)?

PCC16 (chloride) is available in the following size(s): 1 Each.

Is PCC16 (chloride) in stock?

PCC16 (chloride) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PCC16 (chloride)?

PCC16 (chloride) is manufactured by QuantiMol.

What is the estimated delivery time for PCC16 (chloride)?

Estimated delivery time for PCC16 (chloride) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PCC16 (chloride)?

The safety data sheet for PCC16 (chloride) is available here: http://file.medchemexpress.com/batch_PDF/HY-169232/.

PCC16 (chloride)

PCC16 chloride is a CRBN-based cp-PCC with an IC50 value of 102 nM for the degradation of DHHC3. PCC16 chloride has antitumor activity. (Target protein ligand: HY-169235, linker: HY-169236, E3 ligase ligand: HY-10984).

Product Specifications

UNSPSC

12352209

Target

PROTACs

Type

Peptides

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pcc16-chloride.html

Smiles

O=C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CS)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCNC(COCCOCCNC(CCC(NC2=CC=CC(C(N3C4CCC(NC4=O)=O)=O)=C2C3=O)=O)=O)=O)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=C(C=C5)O)NC(C6=C(C(C7=CC=C(N(CC)CC)C=C7OC8=C/9)=C8C=CC9=[N+](CC)\CC)C=CC=C6)=O.[Cl-]

Molecular Formula

C206H322ClN67O60S

Molecular Weight

4764.69

References & Citations

[1]Shi YY, et al. Treating ICB-resistant cancer by inhibiting PD-L1 via DHHC3 degradation induced by cell penetrating peptide-induced chimera conjugates. Cell Death Dis. 2024 Sep 30;15 (9) :701.