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Toltrazuril sulfoxide

Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites[1].

Product Specifications

CAS Number

[69004-15-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/toltrazuril-sulfoxide.html

Purity

99.55

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(N(C1=CC=C(OC2=CC=C(S(C(F)(F)F)=O)C=C2)C(C)=C1)C(N3)=O)N(C)C3=O

Molecular Formula

C18H14F3N3O5S

Molecular Weight

441.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Jong-Hwan Lim, et al. Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs. J Vet Med Sci. 2010 Aug;72 (8) :1085-7.|[2]H Mehlhorn, et al. Toltrazuril effective against a broad spectrum of protozoan parasites. Parasitol Res. 1988;75 (1) :64-6.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Coccidia

Available Sizes

Curated Selection

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