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(-) -Blebbistatin (GMP)

(-) -Blebbistatin (GMP) is (-) -Blebbistatin produced by using GMP guidelines. (-) -Blebbistatin (GMP) is a selective inhibitor of the ATPase activity of non-muscle myosin II[1][2].

Product Specifications

CAS Number

856925-71-8

UNSPSC

12352005

Target

Myosin

Type

Reference compound

Related Pathways

Cytoskeleton

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/minus-blebbistatin-gmp.html

Smiles

CC1=CC=C(N=C(N(C2=CC=CC=C2)CC3)[C@]3(O)C4=O)C4=C1

Molecular Formula

C18H16N2O2

Molecular Weight

292.33

References & Citations

[1]Cristina Lucas‐Lopez, et al. Absolute Stereochemical Assignment and Fluorescence Tuning of the Small Molecule Tool, (–) ‐Blebbistatin.|[2]Ponsaerts R, et al. The myosin II ATPase inhibitor blebbistatin prevents thrombin-induced inhibition of intercellularcalcium wave propagation in corneal endothelial cells. Invest Ophthalmol Vis Sci. 2008 Nov;49 (11) :4816-27.

Shipping Conditions

Room temperature

Scientific Category

GMP Small Molecules

Clinical Information

No Development Reported

Frequently Asked Questions

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