ML132
ML132 (NCGC-00183434) is a selective caspase 1 inhibitor with an IC50 of 34.9 nM. ML132 shows good stability that can be utilized as molecular probes of caspase 1. ML132 can be used for research in the field of anti-cancer and anti-inflammatory[1].
Product Specifications
CAS Number
[1230628-71-3]
Product Name Alternative
NCGC-00183434
UNSPSC
12352005
Target
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ML132.html
Purity
98.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC(C(N[C@@H](C(C)(C)C)C(N2CCC[C@H]2C(N[C@@H](CC(O)=O)C#N)=O)=O)=O)=CC=C1N
Molecular Formula
C22H28ClN5O5
Molecular Weight
477.94
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light, stored under nitrogen
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 1; Caspase 4; Caspase 5; Caspase 8; Caspase 9
Available Sizes
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