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EZH2 / KMT6 (EZH2/2536), CF488A conjugate, 0.1mg/mL

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

Enhancer of zeste 2 polycomb repressive complex 2 subunit; Enhancer of zeste homolog 2 (EZH2) ; ENX1; Enx1h; EZH2b; Histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; Lysine N-methyltransferase 6; WVS; WVS2

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

EZH2

Gene ID

2146

NCBI Gene ID

444082

UniProt

Q15910

Swiss Prot

Q15910

Host

Mouse

Species Reactivity

Human

Reactivity

EZH2|KMT6

Immunogen

Recombinant full-length human EZH2 protein

Target Antigen

EZH2 | KMT6

Clonality

Monoclonal

Clone

EZH2/2536

Type

Primary

Source

Animal

Origin

Animal

Applications

WB (verified)

Positive Control

MCF7, HeLa, U-2 OS or HEK-293 whole cell lysates. Human tonsil, testis or prostate tissue.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

81-102 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG2a, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF488A

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