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P73 (Tumor Suppressor) (P73/2531), 0.2mg/mL

P73 shares considerable sequence similarity with the widely-studied tumor suppressor gene p53. The p73 gene maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, unlike p53, p73 does not appear to be activated by DNA damaging agents. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

P53-like transcription factor; p53-related protein; p73; TP73; Tumor protein p73

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

TP73

Gene ID

7161

NCBI Gene ID

697294; 706990

UniProt

O15350

Swiss Prot

O15350

Host

Mouse

Species Reactivity

Human

Reactivity

P73

Immunogen

Recombinant full-length human TP73 protein

Target Antigen

p73

Clonality

Monoclonal

Clone

P73/2531

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified)

Positive Control

HeLa, Jurkat, HEK293 cell lysates. Human kidney or bladder carcinoma.

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

73 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG2b, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

Conjugate

Purified, with BSA

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