Dihydrokavain (Standard)

Dihydrokavain (Standard) (7,8-Dihydrokawain (Standard) ) is the analytical standard of Dihydrokavain (HY-N0920) . This product is intended for research and analytical applications. Dihydrokavain is a natural kavalactone compound. Dihydrokavain inhibits COX-1, COX-2, CYP2C9 (IC50 = 130.95 μM), CYP2C19 (IC50 = 10.05 μM) and CYP3A4 (IC50 = 78.59 μM) . Dihydrokavain reduces TNFα secretion. Dihydrokavain shows analgesic and anxiolytic effects.

Product Specifications

CAS Number

[587-63-3]

Product Name Alternative

7,8-Dihydrokawain (Standard) ; 7,8-Dihydrokavain (Standard) ; Marindinin (Standard)

UNSPSC

12352005

Target

COX; Cytochrome P450; Reference Standards

Type

Reference Standards

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Others

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dihydrokavain-standard.html

Smiles

O=C1C=C(OC)C[C@H](CCC2=CC=CC=C2)O1

Molecular Formula

C14H16O3

Molecular Weight

232.28

References & Citations

[1]Feltenstein MW, et al. Anxiolytic properties of Piper methysticum extract samples and fractions in the chick social-separation-stress procedure. Phytother Res. 2003 Mar;17 (3) :210-6.