CD50 / ICAM3 (CG106), Biotin conjugate, 0.1mg/mL
Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI) . CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
CD50; CDW 50; CDw50; ICAM 3; ICAM-3; ICAM-R; ICAM3; ICAM3_HUMAN; ICAMR; Intercellular adhesion molecule 3
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ICAM3
Gene ID
3385
NCBI Gene ID
654563
UniProt
P32942
Swiss Prot
P32942
Host
Mouse
Species Reactivity
Human
Reactivity
CD50|ICAM3
Immunogen
Stimulated human leukocytes
Target Antigen
CD50 | ICAM3
Clonality
Monoclonal
Clone
CG106
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published) |ELISA (published)
Field of Research
Immunology
Positive Control
HL-60 or THP-1 cells. Lymph node and tonsil
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
110-160 kDa
References & Citations
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Product Datasheet
https://cdn.gentaur.com/products/37/7639301/datasheet/bncb2216-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/68dd0297061270361e100794/msds/bncb2216-500.pdf
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
CAS Number
9007-83-4
Conjugate
Biotin
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