CLEC9A (1F6), CF647 conjugate, 0.1mg/mL

This Mab recognizes Mouse DNGR-1, which is also known as CLEC9A, which is a highly specific marker of the CD8a and the CD103 DC subsets, as well as a receptor able to recognize a preformed signal exposed on necrotic cells. In peripheral blood, it is highly restricted on the surface of BDCA31 () dendritic cells and on a small subset of CD14 () and CD16 (-) monocytes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

C type lectin domain family 9; member A; C-type lectin domain family 8 member A; CLEC9A; DNGR1; HEEE9341; PRO34046; UNQ9341; CD370

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene ID

232414

NCBI Gene ID

391518

UniProt

Q8RU4

Swiss Prot

Q8RU4

Host

Rat

Species Reactivity

Mouse

Reactivity

CLEC9A

Immunogen

RBL-2H3 cells expressing Mouse CLEC9A fused to an HA epitope.

Target Antigen

CLEC9A

Clonality

Monoclonal

Clone

1F6

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (published) |Functional studies (published)

Positive Control

Mouse spleen.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

27 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Nature (2009) 458(7240): 899-903. (functional studies) J Immunol (2015) 195:5066-5076. (Flow, surface)