GMP IL-18, Human (HEK293, His)
IL-18 protein is a pro-inflammatory cytokine that plays a critical role in epithelial barrier repair and polarized immune responses involving Th1 cells and NK cells. After binding to IL18R1 and IL18RAP, it forms a signaling ternary complex that activates NF-kappa-B, leading to the synthesis of inflammatory mediators. GMP IL-18 Protein, Human (HEK293, His) is the recombinant human-derived IL-18 protein, expressed by HEK293 , with C-6*His labeled tag.
Product Specifications
Product Name Alternative
GMP IL-18 Protein, Human (HEK293, His), Human, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/gmp-il-18-protein-human-hek293-his.html
Purity
97.30
Smiles
Molecular Formula
3606 (Gene_ID) Q14116-1 (Y37-D193) (Accession)
Molecular Weight
Approximately 17-25 kDa, based on SDS-PAGE under reducing conditions.
References & Citations
[1]Robertson SE, et al., Expression and alternative processing of IL-18 in human neutrophils. Eur J Immunol. 2006 Mar;36 (3) :722-31.
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins
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