TNF-α/IL-1β-IN-1
TNF-α/IL-1β-IN-1 (compund 11a) is an anti-inflammatory agent that reduces the expression of TNF-α and IL-1β, inhibits oxidative stress and cardiomyocyte apoptosis, has good activity against septic myocardial injury, and improves myocardial blood supply in vivo[1].
Product Specifications
UNSPSC
12352005
Target
Interleukin Related; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tnf-α-il-1β-in-1.html
Smiles
CC(C)([C@]1([H])CC[C@@]([C@@]2(CC[C@]3(CC[C@](C(O)=O)(C[C@]3(C2=C4)[H])C)C)C)5C)[C@H](CC[C@]1(C)[C@@]5([H])C4=O)OC(CN6CCN(C(C7=CC=CO7)=O)CC6)=O
Molecular Formula
C41H58N2O7
Molecular Weight
690.91
References & Citations
[1]Li W, Peng Y, et al. Discovery and synthesis of novel glyrrhizin-analogs containing furanoylpiperazine and the activity against myocardial injury in sepsis. Bioorg Chem. 2024 Dec;153:107846.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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