Anti-HIV-1 gp120 Antibody
Mouse Monoclonal Antibody specific to HIV-1 gp120 (PNDmn)
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Anti-HIV-1 gp120 (PNDmn) Mouse Monoclonal Antibody
Host
Mouse
Reactivity
Hiv-1
Immunogen
Recombinant gp120 (MN strain), a CCR5 and X4 tropic strain.
Target
HIV-1 gp120
Clonality
Monoclonal
Isotype
IgG1
Type
Antibody
Applications
ELISA
Field of Research
Infectious Disease
Purification Method
Ion exchange-purified
Dilution
Reconstitute with sterile H2O. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Format
Purified
Form
Lyophilized
Buffer
Phosphate Buffered Saline
Additionnal Information
ELISA: use at 1-5ug/ml for binding to recombinant gp120.In vitro virus neutralization: <br><br>End user should determine optimal concentrations.
Storage Conditions
This antibody is stable for at least one year. Store lyophilized product at 4°C. After reconstitution, aliquot and store at -20°C. Avoid multiple freeze-thaw cycles.
Specificity
HIV-1 gp120 (PNDmn)
Formulation
PBS, pH 7.4, Lyophilized
Buffer pH
pH 7.4
Target Background
Human immunodeficiency virus (HIV) is a retrovirus that infects CD4+ T cells, macrophages and dendritic cells leaving infected individuals susceptible to various opportunistic infections. HIV is a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses are transmitted as single-stranded, positive- sense, enveloped RNA viruses. Upon entry into a target cell, viral RNA is converted to double-stranded DNA by a virally encoded reverse transcriptase. Viral DNA is integrated into host cellular DNA by a virally encoded integrase. The virus may become latent or may continue to infect other susceptible cells.
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