CD3e, Mouse (145-2C11), Biotin conjugate, 0.1mg/mL

CD3 chains. CD3 plays a critical role in TCR signal transduction, T-cell activation, and antigen recognition by binding the peptide/MHC antigen complex. The 145-2C11 antibody is useful for in vitro blocking and activation assays, as well as apoptosis induction and in vivo T-cell depletion. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex) ; CD3e molecule; epsilon (CD3-TCR complex) ; IMD18; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

Cd3e (Mouse)

Gene ID

12501

NCBI Gene ID

210361

UniProt

P22646

Swiss Prot

P22646

Host

Armenian Hamster

Species Reactivity

Mouse

Reactivity

CD3e

Immunogen

H2Kb specific Mouse cytotoxic T lymphocyte clone BM10 37

Target Antigen

CD3e

Clonality

Monoclonal

Clone

145-2C11

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (published) |Functional studies (published) |IP (published)

Positive Control

MPBMC's or Thymus or Lymph Node.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

23 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1987) 84:1374-1378. (Flow, IP) Eur J Immunol (1990) 20: 509-515. (functional studies) J Immunol (2003) 171:2496-2503. (Flow; IP; functional studies)