Cytokeratin, Multi (Epithelial Marker) (KRT/1877R), CF405S conjugate, 0.1mg/mL
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6. 0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 52 kDa (CK8) ; 56. 5 kDa (CK10) ; 53 kDa (CK13) and 45 kDa (CK18) . This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID
3851; 3852; 3853; 3854; 286887; 3856; 3858; 3860; 3875
UniProt
P02538; P04259; P13647; P19013; P48668
Swiss Prot
P02538 ; P04259 ; P13647 ; P19013 ; P48668
Host
Rabbit
Species Reactivity
Cow,Frog,Goat,Guinea pig,Human,Monkey,Mouse,Pig,Rat
Reactivity
Cytokeratin, Multi
Immunogen
Keratin-enriched preparation from cultured human epithelial cells
Target Antigen
Cytokeratin, Multi
Clonality
Recombinant Monoclonal
Clone
KRT/1877R
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
A431 cells, Skin, Colon carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
Multiple
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Product Datasheet
https://cdn.gentaur.com/products/37/7635562/datasheet/bnc041877-500.pdf
Product MSDS
https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
CAS Number
9007-83-4
Conjugate
CF405S
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