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Anti-Cytokeratin, Multi (Epithelial Marker)(rKRT/457)

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6. 0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56. 5 kDa (CK10); 53 kDa (CK13) and 45 kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene ID

3851; 3852; 3853; 3854; 286887; 3856; 3858; 3860; 3875

UniProt

P02538; P04259; P13647; P19013; P48668

Cellular Locus

Cytoskeleton

Host

Mouse

Species Reactivity

Cow,Frog,Goat,Guinea pig,Human,Monkey,Mouse,Pig,Rat

Immunogen

Keratin-enriched preparation from cultured human epithelial cells

Target Antigen

Cytokeratin, Multi

Clonality

Recombinant Monoclonal

Isotype

IgG1 κ

Clone

rKRT/457

Conjugation

Purified, with BSA

Source

Animal

Applications

IHC, FFPE (verified)

Validated Applications

IHC,FFPE

Field of Research

Cancer, Cytoskeleton

Positive Control

A431 cells, Skin, Colon carcinoma

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

Multiple

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7635558/datasheet/bnub1876-100.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7635558/msds/bnub1876-100.pdf

CAS Number

9007-83-4

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