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Anticancer agent 216

Anticancer agent 216 (34A) is a Camptothecin compound, with IC50 values of 9.6 nM and 11.6 nM in MCF-7 cells and MDA-MB-231 cells, respectively[1].

Product Specifications

CAS Number

[2916406-02-3]

UNSPSC

12352005

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-216.html

Smiles

C[C@@H](C1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51)N

Molecular Formula

C23H21N3O6

Molecular Weight

435.43

References & Citations

[1]Furao Zhang, et al. Camptothecin compound, preparation method therefor and use thereof. Patent. WO2023030364.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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