Myristoyl-MEK1 Derived Peptide Inhibitor 1

Myristoyl-MEK1 Derived Peptide Inhibitor 1 is the myristoylated form of the MEK1 Derived Peptide Inhibitor 1 (HY-P4133) . Myristoyl-MEK1 Derived Peptide Inhibitor 1 inhibits ERK activation with an IC50 of 10 μM[1].

Product Specifications

CAS Number

[427884-64-8]

UNSPSC

12352209

Target

ERK

Type

Peptides

Related Pathways

MAPK/ERK Pathway; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/myristoyl-mek1-derived-peptide-inhibitor-1.html

Solubility

H2O

Smiles

O=C([C@H]1N(CCC1)C([C@H](CCSC)NC(CCCCCCCCCCCCC)=O)=O)N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H]([C@H](O)C)C(N3[C@@H](CCC3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N4[C@@H](CCC4)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C82H144N18O18S

Molecular Weight

1702.20

References & Citations

[1]Kelemen BR, et al. Selective in vivo inhibition of mitogen-activated protein kinase activation using cell-permeable peptides. J Biol Chem. 2002 Mar 8;277 (10) :8741-8.