Piperidine-4-carbaldehyde
Piperidine-4-carbaldehyde (Piperidine-4-carboxaldehyde) is a PROTAC Linker. Piperidine-4-carbaldehyde can be used to optimize combined with the target protein affinity, thus improve the PROTAC the molecular degradation efficiency. Piperidine-4-carbaldehyde can be used in the CDK2 PROTACs (HY-161708) [1].
Product Specifications
CAS Number
[50675-20-2]
Product Name Alternative
Piperidine-4-carboxaldehyde
UNSPSC
12352005
Hazard Statement
H315-H319-H411
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/piperidine-4-carbaldehyde.html
Smiles
O=CC1CCNCC1
Molecular Formula
C6H11NO
Molecular Weight
113.16
Precautions
P264-P273-P280-P302+P352-P362-P391-P501
References & Citations
[1]Wu M, et al. Discovery of a potent CDKs/FLT3 PROTAC with enhanced differentiation and proliferation inhibition for AML[J]. European Journal of Medicinal Chemistry, 2024: 116539.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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