NCX-6560

NCX-6560 is an orally active nitric oxide releasing derivative of atorvastatin that inhibits cholesterol biosynthesis and has anti-inflammatory and antithrombotic activity[1].

Product Specifications

CAS Number

[803728-45-2]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ncx-6560.html

Smiles

O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC(OCCCCO[N+]([O-])=O)=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4

Molecular Formula

C37H42FN3O8

Molecular Weight

675.74

References & Citations

[1]Momi S, et al. NCX 6560, a nitric oxide-releasing derivative of atorvastatin, inhibits cholesterol biosynthesis and shows anti-inflammatory and anti-thrombotic properties. Eur J Pharmacol. 2007 Sep 10;570 (1-3) :115-24.