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Afloqualone (Standard)

Afloqualone (Standard) is the analytical standard of Afloqualone. This product is intended for research and analytical applications. Afloqualone (HQ-495) is an orally active central muscle relaxant and antivertiginous agent that can increase the sensitivity of GABA receptors in neurons of the lateral vestibular nucleus. Afloqualone (HQ-495) can be used in the research of low back pain and neck-arm-shoulder syndrome[1][2].

Product Specifications

CAS Number

56287-74-2

Product Name Alternative

HQ-495 (Standard)

UNSPSC

12352005

Target

GABA Receptor; Reference Standards

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/afloqualone-standard.html

Smiles

O=C1N(C2=CC=CC=C2C)C(CF)=NC3=C1C=C(N)C=C3

Molecular Formula

C16H14FN3O

Molecular Weight

283.30

References & Citations

[1]T Ochiai, et al. Pharmacological studies on 6-amino-2-fluoromethyl-3- (O-tolyl) -4 (3H) -quinazolinone (afloqualone), a new centrally acting muscle relaxant. (II) Effects on the spinal reflex potential and the rigidity. Jpn J Pharmacol. 1982 Jun;32 (3) :427-38.|[2]Y Kudo, et al. Effects of afloqualone on vestibular nystagmus and the lateral vestibular nucleus. Jpn J Pharmacol. 1989 Aug;50 (4) :515-9.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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