CLEC1B/CLEC-2, Mouse (HEK293, Fc)

Product Specifications

UNSPSC Description

The CLEC1B/CLEC-2 protein serves as a platelet receptor for PDPN. When activated, it signals through SRC and SYK kinases, activating PLCG2. CLEC1B forms homodimers and interacts with RACK1, promoting its ubiquitination and degradation. It also interacts with SYK and PDPN, independently of glycosylation, activating CLEC1B/CLEC-2. CLEC1B/CLEC-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC1B/CLEC-2 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CLEC1B/CLEC-2 Protein, Mouse (HEK293, Fc) is 177 a.a., with molecular weight of 50-65 kDa.

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/clec-2-clec1b-protein-mouse-hek293-fc.html

Purity

98.0

Smiles

MSVTQQKYLL AEKENLSATL QQLAKKFCQE LIRQSEIKTK STFEHKCSPC ATKWRYHGDS CYGFFRRNLT WEESKQYCTE QNATLVKTAS QSTLDYIAER ITSVRWIGLS RQNSKKDWMW EDSSVLRKNG INLSGNTEEN MNCAYLHNGK IHPASCKERH YLICERNAGM TRVDQLL