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CD8B (Cytotoxic / Suppressor T-Cell Marker) (CBB/1595), 0.2mg/mL

The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

CD8 antigen 37kDa chain; CD8 antigen; beta chain; CD8 antigen; beta polypeptide 1 (p37) ; CD8 antigen; beta polypeptide 1; CD8B; LEU2; LYT3; OX 8 membrane antigen; p37; T cell surface glycoprotein CD8 beta chain

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

CD8B

Gene ID

926

NCBI Gene ID

405667

UniProt

P10966

Swiss Prot

P10966

Host

Mouse

Species Reactivity

Bovine,Goat,Sheep

Reactivity

CD8b

Immunogen

Antibody was raised against bovine CD8b.

Target Antigen

CD8b,

Clonality

Monoclonal

Clone

CBB/1595

Type

Primary

Source

Animal

Origin

Animal

Positive Control

HuT78 or hPBL. Tonsil

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

32 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

Conjugate

Purified, with BSA

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