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BEST2 rabbit pAb

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008]

UniProt

Q8NFU1

Swiss Prot

Q8NFU1

Reactivity

Mouse; Rat

Immunogen

Synthetic Peptide of BEST2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF

Dilution

WB: 1:500-1000 IHC: 1:200-500

Molecular Weight

50kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

50kD

Fragment

IgG

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Other Product Names

Bestrophin-2; Vitelliform macular dystrophy 2-like protein 1

Gene ID (Human)

54831

Available Sizes

Curated Selection

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