CJ-21,058
CJ-21,058 is a potent SecA inhibitor with an IC50 value of 15 µg/mL. CJ-21,058 inhibits ATP-dependent translocation of precursor proteins across a bacterial cell membrane. CJ-21,058 shows antibacterial activity against Gram-positive bacteria[1].
Product Specifications
CAS Number
[405072-57-3]
UNSPSC
12352005
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cj-21-058.html
Smiles
O/C([C@@]([C@@](CC[C@H]1C)([H])[C@](C1)([H])C=C2C)([C@@H]2/C=C/C)C)=C(C(N3C)=O)\C([C@@H]3CO)=O
Molecular Formula
C23H33NO4
Molecular Weight
387.51
References & Citations
[1]Sugie Y, et al. CJ-21,058, a new SecA inhibitor isolated from a fungus. J Antibiot (Tokyo) . 2002 Jan;55 (1) :25-9.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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