PFM03
PFM03 is a MRE11 Endonuclease inhibitor. PFM03 regulates DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) [1].
Product Specifications
CAS Number
1558598-48-3
UNSPSC
12352005
Target
Endonuclease
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pfm03.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(/C=C2C(N(C(C)CC)C(S/2)=S)=O)C=C1
Molecular Formula
C14H15NO2S2
Molecular Weight
293.40
References & Citations
[1]Shibata A, et al. DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Mol Cell. 2014 Jan 9;53 (1) :7-18.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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