MAGL-IN-20

MAGL-IN-20 (compound ±34) is a reversible monoacylglycerol lipase (MAGL) inhibitor. MAGL-IN-20 exhibits appreciable antiproliferative activities against several cancer cells, including H460, HT29, CT-26, Huh7 and HCCLM-3.[1].

Product Specifications

CAS Number

[2607107-76-4]

UNSPSC

12352005

Target

MAGL

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/magl-in-20.html

Smiles

C[C@H]1[C@@H](C)N(C(C2=CC=CC3=C2C=CC=C3)=O)CCN1C4=CC=CC=C4

Molecular Formula

C23H24N2O

Molecular Weight

344.45

References & Citations

[1]Yu Q, et al. Design, synthesis and biological evaluation of naphthyl amide derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors. Bioorg Med Chem. 2024 Sep 1;111:117844.