Lys-Arg-Thr-Leu-Arg-Arg

Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C[1].

Product Specifications

CAS Number

[121284-21-7]

Product Name Alternative

KRTLRR

UNSPSC

12352209

Target

EGFR

Type

Peptides

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/lys-arg-thr-leu-arg-arg.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@H](C(O)=O)CCCNC(N)=N)[C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CCCCN)=O)=O)=O)=O

Molecular Formula

C34H68N16O8

Molecular Weight

829.01

References & Citations

[1]Davis RJ, et, al. Stimulation of epidermal growth factor receptor threonine 654 phosphorylation by platelet-derived growth factor in protein kinase C-deficient human fibroblasts. J Biol Chem. 1987 May 15;262 (14) :6832-41.