Trans, trans-Dibenzylideneacetone
Trans, trans-Dibenzylideneacetone ((E, E) -Dibenzylideneacetone) (compound A1) is a dibenzylideneacetone with a week antimalarial activity. trans, trans-Dibenzylideneacetone inhibits P. falciparum 3D7 strain with an IC50 of 213.41 μM[1].
Product Specifications
CAS Number
[35225-79-7]
Product Name Alternative
(E, E) -Dibenzylideneacetone; trans, trans-Dibenzalacetone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/trans-trans-dibenzylideneacetone.html
Purity
99.87
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/C1=CC=CC=C1)/C=C/C2=CC=CC=C2
Molecular Formula
C17H14O
Molecular Weight
234.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Aher RB, et al. Dibenzylideneacetone analogues as novel Plasmodium falciparum inhibitors. Bioorg Med Chem Lett. 2011 May 15;21 (10) :3034-6.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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