IL-23R, Human (HEK293, Fc)

IL-23R Protein, critical in immune response, forms the interleukin-23 receptor by associating with IL12RB1. Binding to IL23, it activates T-cells, NK cells, and potentially macrophage/myeloid cells through Jak-Stat signaling. Associated with autoimmune diseases and tumorigenesis, IL-23R, in the presence of IL12RB1, forms a heterodimeric IL-23 receptor, interacting with JAK2 and activating STAT3. IL-23R Protein, Human (HEK293, Fc) is the recombinant human-derived IL-23R protein, expressed by HEK293 , with C-hFc labeled tag.

GITNINCSGH IWVEPATIFK MGMNISIYCQ AAIKNCQPRK LHFYKNGIKE RFQITRINKT TARLWYKNFL EPHASMYCTA ECPKHFQETL ICGKDISSGY PPDIPDEVTC VIYEYSGNMT CTWNAGKLTY IDTKYVVHVK SLETEEEQQY LTSSYINIST DSLQGGKKYL VWVQAANALG MEESKQLQIH LDDIVIPSAA VISRAETINA TVPKTIIYWD SQTTIEKVSC EMRYKATTNQ TWNVKEFDTN FTYVQQSEFY LEPNIKYVFQ VRCQETGKRY WQPWSSLFFH KTPETVPQVT SKAFQHDTWN SGLTVASIST GHLTSDNRGD