(+) -Igmesine (hydrochloride)
(+) -Igmesine hydrochloride (JO1784) is an orally active and selective σ receptor ligand with neuroprotective and anti-amnesic activities[1].
Product Specifications
Product Name Alternative
JO1784
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/igmesine-hydrochloride.html
Purity
99.0
Solubility
DMSO : 17.79 mg/mL (ultrasonic; warming)
Smiles
[H]Cl.CN(CC1CC1)[C@@](C/C=C/C2=CC=CC=C2)(CC)C3=CC=CC=C3
Molecular Formula
C23H30ClN
Molecular Weight
355.94
References & Citations
[1]O'Neill M, et al. The sigma receptor ligand JO 1784 (igmesine hydrochloride) is neuroprotective in the gerbil model of global cerebral ischaemia. Eur J Pharmacol. 1995 Sep 5;283 (1-3) :217-25.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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