Urethane

Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].

Product Specifications

CAS Number

51-79-6

Product Name Alternative

Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane

UNSPSC

12352211

Hazard Statement

H302, H350

Target

Bacterial; Parasite

Type

Natural Products

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Urethane.html

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC(OCC)=O

Molecular Formula

C3H7NO2

Molecular Weight

89.09

Precautions

H302, H350

References & Citations

[1]K J Field, et al. Hazards of urethane (ethyl carbamate) : a review of the literature. Lab Anim. 1988 Jul;22 (3) :255-62.|[2]R E Sotomayor, et al. Mutagenicity, metabolism, and DNA interactions of urethane. Toxicol Ind Health. 1990 Jan;6 (1) :71-108.|[3]Zheng J, et al. Overexpression of PRDX4 Modulates Tumor Microenvironment and Promotes Urethane-Induced Lung Tumorigenesis. Oxid Med Cell Longev. 2020 Dec 28;2020:8262730.|[4]Sozio F, et al. Urethane-induced lung carcinogenesis. Methods Cell Biol. 2021;163:45-57. |[5]Gurley KE, et al. Induction of Lung Tumors in Mice with Urethane. Cold Spring Harb Protoc. 2015 Sep 1;2015 (9) :pdb.prot077446.